On the day before the 2016 New York City Marathon, Dr. Justin Greisberg delivered a lecture on the evolution of the human foot at the 2016 Regional Meeting of the American Association of Anatomists. In addition to discussing the evolutionary adaptations required for walking and running upright, Dr. Greisberg discussed more modern trends in barefoot running and issues affecting endurance runners. Dr. Greisberg joined a distinguished panel of experts, including Columbia Orthopedics residents Drs. Thomas Hickernell and Matthew Grosso, for the day-long program of lectures and practical demonstrations focused on locomotion, running, and assessment & treatment of lower extremity injuries.